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Zoloft is in a class of drugs called selective serotonin reuptake inhibitors. Zoloft affects chemicals in the brain that may become unbalanced and cause depression, panic or anxiety, obsessive or compulsive symptoms, or other psychiatric symptoms.
Zoloft is used to treat depression, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).
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What are the possible side effects of sertraline - Zoloft?

If you experience any of the following serious side effects, stop taking sertraline and contact your doctor immediately or seek emergency medical treatment:

An allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); an irregular heartbeat or pulse; low blood pressure (dizziness, weakness); high blood pressure (severe headache, blurred vision); or chills or fever.

If you experience any of the following less serious side effects, continue taking sertraline and talk to your doctor: headache; tremor, nervousness, or anxiety; nausea, diarrhea, dry mouth, or changes in appetite or weight; sleepiness or insomnia; or decreased sex drive, impotence, or difficulty having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect sertraline - Zoloft?

Do not take sertraline if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred when these medicines have been used together.

Do not take sertraline - Zoloft if you are taking pimozide (Orap). A dangerous drug interaction could result.

Before taking sertraline - Zoloft, tell your doctor if you are taking any of the following medicines: a benzodiazepine such as diazepam (Valium), alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), temazepam (Restoril), triazolam (Halcion), and others; a tricyclic antidepressant such as amitriptyline (Elavil), imipramine (Tofranil), doxepin (Sinequan), nortriptyline (Pamelor), and others; a phenothiazine including chlorpromazine (Thorazine), thioridazine (Mellaril), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), and others; lithium (Lithobid, Eskalith, others) or clozapine (Clozaril); almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); carbamazepine (Tegretol) or phenytoin (Dilantin); warfarin (Coumadin); digoxin (Lanoxin); cimetidine (Tagamet, Tagamet HB); or bupropion (Wellbutrin, Zyban).

You may not be able to take sertraline, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Do not take the Zoloft Oral Concentrate without first talking to your doctor if you are taking disulfiram (Antabuse). The oral solution contains alcohol, which may interact with disulfiram.

Drugs other than those listed here may also interact with sertraline. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


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