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Zocor blocks the production of cholesterol (a type of fat) in the body and  is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Zocor is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
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What are the possible side effects of simvastatin - Zocor?

If you experience any of the following serious side effects, stop taking simvastatin and call your doctor immediately:

An allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); muscle aches, pain or weakness; "flu-like" symptoms; decreased urine or rust-colored urine; blurred vision; or yellowing of your skin or eyes.

Other, less serious side effects may be more likely to occur. Continue to take simvastatin and talk to your doctor if you experience gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea; cough; headache; or insomnia.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect simvastatin - Zocor?

Do not take simvastatin without first talking to your doctor if you are taking any of the following medicines: cyclosporine (Sandimmune, Neoral); gemfibrozil (Lopid); niacin (Nicolar, Nicobid, Nicotinex, others); nefazodone (Serzone); clarithromycin (Biaxin); erythromycin (E-Mycin, E.E.S., Ery-Tab, Ilotycin, Eryc, PCE, Ilosone, others); or itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral).

These medications may interact with simvastatin and damage your muscles.

Before taking simvastatin, tell your doctor if you are taking any of the following medicines: other cholesterol-lowering drugs such as cholestyramine (Questran) or colestipol (Colestid); digoxin (Lanoxin, Lanoxicaps); warfarin (Coumadin); or a protease inhibitor such as amprenavir (Agenerase), indinavir (Crixivan); nelfinavir (Viracept), ritonavir (Norvir), or saquinavir (Invirase, Fortovase).

You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.


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