|What are the possible side effects of
orlistat - Xenical?
Stop taking orlistat and seek emergency medical attention if you
experience a rare allergic reaction including shortness of breath;
closing of your throat; swelling of your lips, tongue, or face; or
Other, less serious side effects are more likely to occur. Continue to
take orlistat and talk to your doctor if you experience oily spotting,
gas with discharge, an urgent need to go to the bathroom, oily or fatty
stools, an oily discharge, an increased number of bowel movements, an
inability to control bowel movements, or orange or brown colored oil in
The bowel changes listed above are a natural effect of blocking fat and
indicate that orlistat is working. They generally occur early in
treatment, particularly after meals containing higher amounts of fat
than are recommended. These symptoms are usually temporary and lessen or
disappear as you continue treatment and keep to your recommended diet of
meals containing 30% fat.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
What other drugs will affect orlistat - Xenical?
Do not take orlistat without first talking to your doctor if you are
taking any of the following medicines: cyclosporine (Neoral,
Sandimmune), or warfarin (Coumadin).
You may not be able to take orlistat, or you may require a dosage
adjustment or special monitoring during your treatment if you are taking
any of the medicines listed above.
Before taking orlistat, tell your doctor if you are taking any of the
following medicines to lower cholesterol: atorvastatin (Lipitor),
cerivastatin (Baycol), fluvastatin (Lescol), lovastatin (Mevacor),
pravastatin (Pravachol), or simvastatin (Zocor).
You may require a dosage adjustment or special monitoring during
treatment if you are taking any of the cholesterol-lowering medicines
Orlistat may decrease your body's absorption of some fat-soluble
vitamins. To ensure adequate nutrition, your doctor may recommend taking
a multivitamin that contains vitamins D, E, K, and beta-carotene. Take
your vitamin supplement once a day, at least 2 hours before or after a
dose of orlistat.
Drugs other than those listed here may also interact with orlistat. Talk
to your doctor and pharmacist before taking or using any other
prescription or over-the-counter medicines.