|What are the possible side effects of
If you experience any of the following serious side effects, stop taking
tramadol and seek emergency medical attention or contact your doctor
An allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives); or seizures.
Other, less serious side effects may be more likely to occur. Continue
to take tramadol and talk to your doctor if you experience dizziness,
drowsiness, or headache; nervousness, tremor, or anxiety; nausea,
vomiting, constipation, or diarrhea; or itching, dry mouth, or sweating.
Tramadol is habit forming. Physical and/or psychological dependence can
occur, and withdrawal effects are possible if the medication is stopped
suddenly after prolonged or high-dose treatment.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
What other drugs will affect tramadol?
Tramadol may increase the risk of seizures especially in patients who
have epilepsy or another seizure disorder. Also, tramadol may increase
the risk of seizures if you are taking any of the following drugs: a
tricyclic antidepressant such as amitriptyline (Elavil), nortriptyline
(Pamelor), doxepin (Sinequan), imipramine (Tofranil), clomipramine
(Anafranil), and others; a monoamine oxidase inhibitor (MAOI) such as
isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine
(Parnate); an antipsychotic medication such as chlorpromazine
(Thorazine), fluphenazine (Prolixin), haloperidol (Haldol), loxapine
(Loxitane), mesoridazine (Serentil), perphenazine (Trilafon),
thioridazine (Mellaril), thiothixene (Navane), and others; a selective
serotonin reuptake inhibitor (SSRI) such as fluoxetine (Prozac),
fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or
citalopram (Celexa); a narcotic pain reliever such as codeine, fentanyl
(Duragesic), hydromorphone (Dilaudid), meperidine (Demerol), hydrocodone
(Vicodin, Lorcet, Lortab, others), morphine (MS Contin, MSIR, RMS,
Roxanol, others), oxycodone (Roxicodone, Percocet, Percodan, others),
propoxyphene (Darvon, Darvocet, others), and others; promethazine
(Phenergan) or prochlorperazine (Compazine); bupropion (Wellbutrin,
Zyban); or cyclobenzaprine (Flexeril).
Do not take tramadol without first talking to your doctor if you are
taking any of the medicines listed above.
Before taking tramadol, tell your doctor if you are taking any of the
following medicines: carbamazepine (Tegretol); quinidine (Quinaglute
Dura-Tabs, Cardioquin, Quinora, others); warfarin (Coumadin); or digoxin
You may not be able to take tramadol, or you may require a dosage
adjustment or special monitoring during treatment if you are taking any
of the medicines listed above.
Tramadol may increase the effects of other drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines, sedatives (used to
treat insomnia), other pain relievers, anxiety medicines, and muscle
relaxants. Tell your doctor about all medicines that you are taking, and
do not take any other prescription or over-the-counter medicines,
including herbal products, without first talking to your doctor during
treatment with tramadol.
Drugs other than those listed here may also interact with tramadol. Talk
to your doctor and pharmacist before taking any prescription or
over-the-counter medicines, including herbal products.