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Synthroid is a naturally occurring hormone produced by your thyroid. It is important for normal energy and metabolism. For a variety of reasons, your body may not produce enough of this hormone on its own. In these cases, levothyroxine is taken to replace your body's natural thyroid hormone. Synthroid is also used to prevent and treat goiter (growth or enlargement of the thyroid gland). Causes of goiter include hormonal imbalances, radiation, surgery, and cancer.
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What are the possible side effects of levothyroxine?

If you experience any of the following serious side effects, stop taking levothyroxine and seek emergency medical attention:

An allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); vomiting; or chest pain, irregular heartbeat, shortness of breath.

Other, less serious side effects may be more likely to occur. Continue to take levothyroxine and talk to your doctor or try another similar medication if you experience tremor, nervousness, or irritability; headache; insomnia; diarrhea, changes in appetite, or weight loss; leg cramps; menstrual irregularities; or fever, sweating, or heat sensitivity.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect levothyroxine?

Other drugs may bind to levothyroxine and reduce the amount that is available in your body, making it less effective. Separate levothyroxine doses from the following medicines: antacids that contain aluminum; the prescription ulcer medicine sucralfate (Carafate); the cholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid); and ferrous sulfate (a type of iron supplement).

Drugs other than those listed here may also interact with levothyroxine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.


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