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Prozac is in a class of drugs called selective serotonin reuptake inhibitors. It affects chemicals in the brain that may become unbalanced and cause depression or mood disturbances, eating disorders, or obsessive or compulsive symptoms.
Prozac is used to treat depression, obsessive-compulsive disorders, panic disorder, and bulimia (binge eating and purging). Prozac is also used to treat premenstrual dysphoric disorder (PMDD), symptoms of which occur in the week or two before a woman's menstrual period and commonly include irritability, mood swings, and tension as well as the physical symptoms of bloating and breast tenderness.
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What are the possible side effects of fluoxetine?

If you experience any of the following serious side effects, stop taking fluoxetine and contact your doctor immediately or seek emergency medical treatment:

An allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); an irregular heartbeat or pulse; low blood pressure (dizziness, weakness); high blood pressure (severe headache, blurred vision); chills or fever; unusual bleeding or bruising; a rash or hives.

If you experience any of the following less serious side effects, continue taking fluoxetine and talk to your doctor: headache, tremor, nervousness, or anxiety; difficulty concentrating; nausea, diarrhea, dry mouth, or changes in appetite or weight; weakness; increased sweating; sleepiness or insomnia; or decreased sex drive, impotence, or difficulty having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect fluoxetine?

Do not take fluoxetine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred when these medicines have been used together. Also, do not take fluoxetine if you are taking thioridazine (Mellaril). Dangerous, even fatal irregular heartbeats may occur if these medicines are taken together. You must wait 5 weeks after stopping fluoxetine before taking thioridazine (Mellaril).

Before taking fluoxetine, tell your doctor if you are taking any of the following medicines: a benzodiazepine such as diazepam (Valium), alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), temazepam (Restoril), triazolam (Halcion), and others; a tricyclic antidepressant such as amitriptyline (Elavil), imipramine (Tofranil), doxepin (Sinequan), nortriptyline (Pamelor), and others; St. John's wort; a phenothiazine such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), and others; lithium (Lithobid, Eskalith, others) or haloperidol (Haldol); almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); carbamazepine (Tegretol) or phenytoin (Dilantin); warfarin (Coumadin); or digoxin (Lanoxin).

You may not be able to take fluoxetine, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with fluoxetine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


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