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Erythromycin is in a class of drugs called macrolide antibiotics that fights bacteria in the body and is used to treat many different types of bacterial infections, such as tonsillitis, bronchitis, pneumonia, whooping cough, Legionnaire's disease, chlamydia, gonorrhea, skin infections, and others.
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What are the possible side effects of erythromycin?

If you experience any of the following serious side effects, stop taking erythromycin and seek emergency medical attention or contact your doctor immediately:

A allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).

Other, less serious side effects may be more likely to occur. Continue to take erythromycin and talk to your doctor if you experience nausea, vomiting, diarrhea, or abdominal pain (take erythromycin with food or milk if you experience any of these side effects); dizziness, fatigue, or headache; vaginal yeast infection; a rash; or increased sensitivity to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect erythromycin?

Do not take erythromycin if you are taking any of the following medicines: terfenadine (Seldane, Seldane-D); astemizole (Hismanal); cisapride (Propulsid); or pimozide (Orap).

Erythromycin may interact with these medicines resulting in dangerous or life-threatening irregular heartbeats.

Before taking erythromycin, tell your doctor if you are taking digoxin (Lanoxin); disopyramide (Norpace); warfarin (Coumadin); theophylline (Theo-Dur, Theobid, and others); midazolam (Versed) or triazolam (Halcion); ergotamine (Ercaf, Cafergot, Ergostat, Ergomar) or dihydroergotamine (D.H.E. 45, Migranal); carbamazepine (Tegretol); phenytoin (Dilantin); valproic acid (Depakote, Depakene); tacrolimus (Prograf); cyclosporine (Sandimmune, Neoral); lovastatin (Mevacor) or simvastatin (Zocor); bromocriptine (Parlodel); or other antibiotics.

You may not be able to take erythromycin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with erythromycin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


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