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Ampicillin (or amoxicillin) is effective against susceptible bacteria causing infections of the middle ear, sinuses, bladder, and kidney...
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SIDE EFFECTS:

Allergic reactions are relatively common side effects during therapy with any of the penicillins. These reactions can range from rashes to anaphylaxis, a severe condition in which there may be shock and even death. Rashes occur more frequently with ampicillin than with the other penicillins. The incidence of rash with ampicillin seems to be higher in patients with viral illnesses, such as mononucleosis. Patients with a history of allergic reaction to any other penicillin should not receive ampicillin. Persons who are allergic to the cephalosporin class of antibiotics which is more distantly related to the penicillins (e.g., Ceclor, Keflex, Cefzil) may or may not be allergic to penicillins.
Nausea, vomiting, loss of appetite, diarrhea, and abdominal pain are commonly reported gastrointestinal side effects during ampicillin therapy, but are rarely severe. Diarrhea appears to occur more frequently with ampicillin than with the other penicillins.

DRUG INTERACTIONS:

Probenecid (Benemid), causes an increase in the amount of ampicillin in the body. This interaction may be used to advantage. (See Dosing.) Use of ampicillin with allopurinol can increase the incidence of drug-related skin rash. Very high doses of ampicillin (at least 1 gram or 1000 mg) can decrease the effect of atenolol (Tenormin) by decreasing its concentration in the blood. Similarly, ampicillin, even in normal doses, can decrease the effectiveness of birth control pills by decreasing the blood concentrations of the estrogens in the birth control pills.


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